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Image Search Results
Journal: Heliyon
Article Title: Application of transcritical CO 2 heat pumps to boiler replacement in low impact refurbishment projects
doi: 10.1016/j.heliyon.2024.e26929
Figure Lengend Snippet: Simscape's CO 2 properties.
Article Snippet: The study is based on a simulation model built in the
Techniques:
Journal: Heliyon
Article Title: Application of transcritical CO 2 heat pumps to boiler replacement in low impact refurbishment projects
doi: 10.1016/j.heliyon.2024.e26929
Figure Lengend Snippet: Overall simscape model.
Article Snippet: The study is based on a simulation model built in the
Techniques:
Journal: bioRxiv
Article Title: GRN_modeler: An Intuitive Tool for Constructing and Evaluating Gene Regulatory Networks and its Applications to Oscillators and a Light Biosensor
doi: 10.1101/2024.12.18.629005
Figure Lengend Snippet: Applications of three different node models implemented in GRN modeler. I) The repressilator a) Topology of the repressilator. b) Topology of the circuit in the interface generated by the make graph() method: the red dots N 1 , N 2 , and N 3 represent the nodes in the circuit. The red arrows denote the directed edges of the graph, illustrating the repression interactions between nodes. Additionally, the yellow dots N 1 |− N 3 , N 2 |− N 1 , and N 3 |− N 2 represent the regulatory interactions. For example, N 1 |− N 3 denotes that node N 1 is repressed by N 3 . c) Deterministic and d) stochastic simulations of the repressilator using the Elowitz model, as described in Table S2 in the SI. The detailed information about the model is available in the SI, specifically in the file “repressilator.html”. II) Re-designed repressilator for an independent modulation of amplitude and frequency. a) Topology of the re-designed repressilator. “C” and “L” are proteases, “I 1 ” and “I 2 ” external inducers, “U” and “Y” transcription factors activating N 4 and N 2 respectively. The dotted gray lines indicate which proteins are degraded by the proteases. b) Topology of the circuit in the interface. c) The effect of the inducers on the amplitude of N 4 . d) The effect of the inducers on the time period of N 4 . The detailed information about the model is available in the SI, specifically in the file “Tomazou.html”. III) The CRISPRlator circuit. a) Topology of the CRISPRlator. b) Topology of the circuit in the interface. For example, N 1 NOHILL |− N 3 denotes that node N 1 is repressed by N 3 through an input named NOHILL, which corresponds to the CRISPRi interaction in the node model. This repression is incorporated into the system by introducing new reactions (R 6 and R 7 in Table S4), where the dCas:sgRNA N3 complex binds to DNA N1 , inhibiting transcription at node N 1 . c) Deterministic and d) stochastic simulations of the CRISPRlator generated by the model detailed in Table S4 in the SI. The detailed information about the model is available in the SI, specifically in the file “CRISPR.html”. The deterministic simulations were fulfilled with the “ode15s” solver of MATLAB, while the stochastic simulations were performed using the “adaptivesa” solver of COPASI in every case.
Article Snippet: Our application is based on
Techniques: Generated, CRISPR